A new cannabis study has shed some light on the effects of CBD and THC when used separately and together.
It found that high doses of CBD can, in fact, have slight intoxicating effects.
It also found that low doses of CBD can actually enhance the high caused by THC rather than diminish it, as is commonly thought.
CBD is psychoactive and intoxicating
Contrary to popular belief and how it’s often marketed, CBD is actually psychoactive – it very clearly has an effect on the mind. However, this new study done in Australia has found that it can also
Subjects in the study vaporised five different preparations spaced one week apart, with the following planned contrasts: placebo vs CBD alone (400 mg); THC alone (8 mg) vs THC combined with low (4 mg) or high (400 mg) doses of CBD; a placebo, THC alone (8mg), high-CBD alone (400mg), THC and low-CBD (8mg and 4mg, respectively); and THC and high-CBD (12mg and 400mg, respectively).
They discovered that “CBD [alone] showed some intoxicating properties relative to placebo.”
“[Subjects] felt intoxicated due to distinct feelings of depersonalization, derealization and altered internal and external perceptions,” the
This almost certainly would contribute to feelings of slight intoxication.]
Low dose CBD enhances THC high
The study, published this month in the journal European Archives of Psychiatry and Clinical Neuroscience, also found that low doses of CBD can actually increase the intoxicating effects of THC.
The researchers noted that “the enhancement of intoxication by low-dose CBD was particularly prominent in infrequent cannabis users and was consistent across objective and subjective measures.
“While precise mechanisms remain to be elucidated, the finding that low doses of CBD may potentiate effects of THC has significant implications for consideration of proportions of THC and CBD that may be recommended within plant matter.”
High dose CBD reduces THC high
One widely held notion was confirmed by the study, however: high doses of CBD reduced the intoxicating effects of THC.
This is an important because, as the authors of the study point out, “With cannabis increasingly being used for medicinal purposes, it is important to ensure that harms are minimized in favor of boosting therapeutic properties.
“While intoxication per se is not necessarily harmful overall, it is not welcome by many clinical patients, and it may be harmful in situations such as driving under the influence of cannabis.”